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Recent Publications

Lindquist S., DebBurman S.K., Glover J.R., Kowal A.S., Liu J.J., Schirmer E.C., and Serio T.R. Amyloid fibres of Sup35 support a prion-like mechanism of inheritance in yeast. Biochem Soc Trans 26:486-90 (1998).

Serio T.R., Cashikar A.G., Moslehi J.J., Kowal A.S., and Lindquist S.L. Yeast Prion [ψ+] and Its Determinant, Sup35p. Meth Enz 309: 649-673 (1999).

Serio T.R. and Lindquist S.L. [PSI+] : An Epigenetic Modulator of Translation Termination Efficiency. Ann Rev Cell Dev Biol 15:661-703 (1999).

Serio T.R. and Lindquist S.L. Protein-only inheritance in yeast: something to get [PSI+]-ched about. Trends Cell Biol 10:98-105 (2000).

Serio T.R., Cashikar A.G., Kowal A.S., Sawicki G.J. Moslehi, J.J., Serpell L., Arnsdorf M.F., and Lindquist S.L. Nucleated Conformational Conversion and the Replication of Conformational Information by a Prion Determinant. Science 289:1317-21 (2000)(subject of news and views, Nature Structural Biology 7: 824-6 (2000)

Serio T.R. and Lindquist S.L. [PSI+], Sup35 and Chaperones. Adv Protein Chem 57:335-66 (2001).

Serio T.R., Cashikar A.G., Kowal A.S., Sawicki, G., and Lindquist S.L. Self-Perpetuating Changes in Sup35 Protein Conformation as a Mechanism of Heredity in yeast. in Biochem Soc Symp 68:35-43 (2001).

Serio T.R. and Lindquist S.L. The Yeast Prion [PSI+]:Molecular Insights and Functional Consequences. Adv Protein Chem 59:391-412 (2001).

Satpute-Krishnan P. and Serio T.R. Prion Protein Remodeling Confers An Immediate Phenotypic Switch. Nature 437:262-265 (2005).

Satpute-Krishnan P., Langseth S., and Serio T.R. Hsp104-Dependent Remodeling of Prion Complexes Mediates Protein-Only Inheritance. PLoS Biology 5:e24 (2007).

Pezza J.A. and Serio T.R. Prion Propagation, The Role of Protein Dynamics. Prion 1: 36-43 (2007).

Pezza J.A., Langseth S.X., Yamamoto R.R., Doris S.M., Ulin S.P., Salomon A.R., and Serio T.R. The NatA Acetyltransferase Couples Sup35 Prion Complexes to the [PSI+] Phenotype. Mol Biol Cell Dec. 10 (2008) [epub ahead of print].

Sindi S.S. and Serio T.R. Prion Dynamics and the Quest for the Genetic Determinant in Protein-Only Inheritance. Curr Opin Microbiol (in press).