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publications
Publications related to the work of our SRP will be listed here as they become available. An asterisk (*) identifies formal collaborative publications involving more than one project and/or core. Brown University's SRP members also maintain listings of their publications on departmental pages. To view these listings, use the links marked "departmental page" on the Investigators page of this website.
PROJECT 1: Mechanism of Toxicant-induced Testicular Sensitization
Kim Boekelheide, M.D., Ph.D.
- 2012
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Campion, S.N.,Catlin, N., Houseman, E.A., Hensley, J., Sui, Y., Gaido, K.W., Wu, Z., Boekelheide, K. (2012). Molecular Alterations Underlying the Enhanced Disruption of Spermatogenesis by 2,5-Hexanedione and Carbendazim Co-exposure.
Reprod Toxicol. 33, 382-389.
PMCID: PMC3327768 -
Pacheco, S.E., Anderson, L.M., Boekelheide, K. (2012)
Optimization of a filter-lysis protocol to purify rat testicular homogenates for automated spermatid counting.
J. Androl.
PMID: 22240558 [PubMed - in process] - Pacheco, S.E., Anderson, L.M., Sandrof, M.A., Vantangoli, M.M., Hall, S.J., Boekelheide, K. (2012). Sperm mRNA transcripts are indicators of sub-chronic low dose testicular injury in the Fischer 344 rat. PLoS ONE 7, e44280. doi:10.1371/journal.pone.0044280. PMCID: PMC3432073
- Springer, C., Dere, E., Hall, S.J., McDonnell-Clark, E., Roberts, S.C., Butt, C.M., Stapleton, H.M., Watkins, D.J., McClean, M.D., Webster, T.F., Schlezinger, J.J., Boekelheide, K. (2012). Rodent thyroid, liver, and fetal testis toxicity of the monoester metabolite of bis-(2-ethylhexyl) tetrabromophthalate (TBPH), a novel brominated flame retardant present in indoor dust. Environ. Health Perspect. 120:1711–1719. PMCID: PMC3548273
- *Thompson, M.R., Boekelheide, K. (2012). Multiple environmental chemical exposures to lead, mercury and polychlorinated biphenyls among childbearing-aged women (NHANES 1999–2004): Body burden and risk factors. Env. Res. PMID: 23158727. PMC Journal – In Process
- 2011
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Pacheco SE, Houseman EA, Christensen BC, Marsit CJ, Kelsey KT, Sigman M, Boekelheide K.
Integrative DNA methylation and gene expression analyses identify DNA packaging and epigenetic regulatory genes
associated with low motility sperm.
PLoS ONE
PubMed Listing - 2010
- Boekelheide, K., Campion, S.N. Toxicity testing in the 21st century: using the new toxicity testing paradigm to create a taxonomy of adverse effects. Toxicol Sci. PubMed Listing
- Campion, S.N., Houseman, E.A., Sandrof, M.A., Hensley, J., Sui, Y., Gaido, K.W., Wu, Z., Boekelheide, K. Suppression of Radiation-induced Testicular Germ Cell Apoptosis. II. Gene Array Analysis Reveals Adaptive Changes in Cell Cycle and Cell Death Pathways. Toxicol Sci. PubMed Listing
- Campion, S.N., Sandrof, M.A., Yamasaki, H., Boekelheide, K. Suppression of Radiation-induced Testicular Germ Cell Apoptosis. III. Candidate Gene Analysis Identifies a Role for Fas in the Attenuation of X-ray-induced apoptosis. Toxicol Sci. PubMed Listing
- Yamasaki, H., Sandrof, M.A., Boekelheide, K. Suppression of Radiation-induced Testicular Germ Cell Apoptosis by 2,5-Hexanedione Pretreatment. I. Histopathological Analysis Reveals Stage-Dependence of Attenuated Apoptosis. Toxicol Sci. PubMed Listing
- 2008
- Bryant, B.H., Yamasaki, H., Sandrof, M., Boekelheide, K. Spermatid head retention as a marker of 2,5-hexanedione-induced testicular toxicity in the rat. Toxicol. Pathol. PubMed Listing
- Klysik, J., Theroux, S.J., Sedivy, J.M., Moffit, J.S., Boekelheide, K. Signaling crossroads: The function of Raf kinase inhibitory protein in cancer, the central nervous system. Cell Signal. PubMed Listing
- 2007
- Boekelheide, K. Toxicological Highlight - Mixed Messages. Toxicol. Sci. Online access
- Bryant, B.H., Boekelheide, K. Time-dependent changes in post-mortem testis histopathology in the rat. Toxicol. Pathol. PubMed Listing
- Moffit, J.S., Boekelheide, K., Sedivy, J.M., Klysik, J. Mice lacking Raf kinase Inhibitor Protein-1 (RKIP-1) have altered sperm capacitation and reduced reproduction rates with a normal response to testicular injury. J. Androl. PubMed Listing
- Moffit, J.S., Bryant, B.H., Hall, S.J., Boekelheide K. Dose-dependent effects of Sertoli cell toxicants 2,5-hexanedione, carbendazim, and mono-(2-ethylhexyl) phthalate in adult rat testis. Toxicologic Pathol. PubMed Listing
- Rasoulpour, R.J., Boekelheide, K. NF-kappaB activation elicited by ionizing radiation is proapoptotic in testis. Biol. Reprod. PubMed Listing
- 2006
- Rasoulpour, R.J., Boekelheide, K. The Sycp1-Cre transgenic mouse and male germ cell inhibition of NF-kappa b. J. Androl. PubMed Listing
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PROJECT 2: Toxicity Of Metallic Nanoparticles And Carbon Nanotubes
Agnes Kane, M.D., Ph.D.
- 2012
- *Chen Y, Guo F, Jachak A, Kim SP, Datta D, Liu J, Kulaotos I, Vaslet C, Jang HD, Huang J, Kane A, Shenoy VB, Hurt RH (2012) Aerosol synthesis of cargo-filled graphene nanosacks. Nano Lett. 12(4):1996-2002. PMC3357130
- *Creighton MA, Rangel-Mendez JR, Huang J, Kane AB, Hurt, RH. Graphene Induced Adsorptive and Optical Artifacts During In Vitro Toxicology Assays Small, in press.
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*Liu J, Wang Z, Liu FD, Kane AB, Hurt RH.
Chemical Transformations of Nanosilver in Biological Environments
ACS Nano 6: 9887-99.
PMCID: PMC3508364 -
*Sanchez V, Jachak A, Hurt, RH, Kane AB.
Biological interactions of graphene-family nanomaterials.
Chem. Res. Toxicol. 25: 15-34.
PMCID: PMC3259226 - 2011
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Broaddus, V.C., Everitt, J.I., Black, B., Kane, A.B.
Non-neoplastic and neoplastic endpoints following fiber exposure.
J. Toxicol. And Environ. Health.
PubMed Listing -
*Liu X, Sen S. Liu J, Kulaots I, Geohegan D, Kane AB, Palmore T, Hurt RH.
Antioxidant deactivation on graphene nanocarbon surfaces.
Small.
PubMed Listing -
*Pietruska JR, Liu X, Smith A, McNeil K, Weston P, Zhitkovich A, Hurt RH, Kane AB.
Bioavailability, intracellular mobiliztion of nickel and HIF-1? activation in human lung epithelial cells exposed to metallic nickel and nickel oxide nanoparticles.
Toxicol Sci.
PubMed Listing -
*Sanchez, V.C., Weston, P., Yan, A., Hurt, R.H., Kane, A.B.
A 3-dimensional in vitro model of epithelioid granulomas induced by high aspect ratio nanomaterials.
Particle and Fibre Toxicology.
PubMed Listing -
*Shi X, von dem Bussche A, Hurt RH, Kane AB, Gao H.
Cell entry of one-dimensional nanomaterials occurs by tip recognition and rotation.
Nat. Nanotechnol.
PubMed Listing - 2010
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*Pietruska, J.R., Johnston, T., Zhitkovich, A, Kane A.B.
XRCC1 Deficiency Sensitizes Human Lung Epithelial Cells to Genotoxicity by Crocidolite Asbestos and Libby Amphibole.
Environ Health Perspect.
PubMed Listing -
Lau, B.W., Kane, A.B.
SDF1/CXCL12 is involved in recruitment of stem-like progenitor cells to orthotopic murine malignant mesothelioma spheroids.
Anticancer Res.
PubMed Listing -
*Liu X, Hurt RH, Kane AB.
Biodurability of Single-Walled Carbon Nanotubes Depends on Surface Functionalization.
Carbon N Y.
PubMed Listing - 2009
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*Sanchez, V.C., Pietruska, J.R., Miselis, N.R., Hurt, R.H., Kane, A.B.
Biopersistence and potential adverse health impacts of fibrous nanomaterials: what have we learned from asbestos?
Nanomed Nanobiotechnol.
PubMed Listing - 2008
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*Kane, A.B., Hurt, R.H.
Nanotoxicology: The Asbestos Analogy Revisited.
Nat. Nanotechnol.
PubMed Listing -
*Guo, L., Von Dem Bussche, A., Buechner, M., Kane, A.B., Hurt, R.H. Adsorption of essential micronutrients by carbon nanotubes and its implications for nanotoxicity testing.
Small.
PubMed Listing -
*Liu, X., Guo, L., Morris, D., Kane, A.B., Hurt, R.H. Targeted removal of bioavailable metal as a detoxification strategy for carbon nanotubes.
Carbon.
PubMed Listing - 2007
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*Guo, L., Liu, X., Sanchez, V., Vaslet, C., Kane, A.B., Hurt, R.H.
A window of opportunity: Designing carbon nanomaterials for environmental safety and health. Mater. Sci. Forum.
Online access. -
*Guo, L., Morris, D.G., Liu, X., Vaslet C., Hurt, R.H., Kane, A.B. Iron bioavailability and redox activity in diverse carbon nanotube samples.
Chem. Mater.
Online access. -
*Liu, X., Gural, V., Morris, D., Murray, D., Zhitkovich, A., Kane, A.B., Hurt, R.H. Bioavailability of nickel in single-wall carbon nanotubes.
Adv. Mater.
Online access. -
Pietruska, J.R., Kane, A.B. SV40 oncoproteins enhance asbestos-induced dna double-strand breaks and abrogate senescence in murine mesothelial cells.
Cancer Res.
PubMed Listing -
*Yan, A., Von Dem Bussche, A., Kane, A.B., Hurt, R.H. Tocopheryl polyethylene glycol succinate as a safe, antioxidant surfactant for processing carbon nanotubes and fullerenes. Carbon.
PubMed Listing - 2006
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*Hurt, R.H., Monthioux, M., Kane, A.B. Toxicology of carbon nanomaterials: status, trends, and perspectives on the special issue.
Carbon.
Online access -
*Yan, A., Lau, B.W., Weissman, B.S., Kulaots, I., Yang, N.Y.C., Kane,A.B., Hurt, R.B. Biocompatible hydrophilic supramolecular carbon nanoparticles for cell delivery.
Adv. Mater.
Online access
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PROJECT 3: Genetic Stress and Toxicant-induced Pregnancy Disruption
Surendra Sharma, M.B.B.S., Ph.D.
- 2013
- Thaxton, J., Saito, S., and Sharma, S. (2013). NKG2D Blockade Inhibits Poly(I:C)-Triggered Fetal Loss in Wild Type but Not IL-10-/- Mice. Journal of Immunology, PMC Journal - In Process.
- Sun, Y., Qin, X., Shan, B., Wang, W., Zhu, Q., Sharma, S., Wu, J., and Lin, Y. (2013). Differential Effects of CpG-TLR9 Axis on Pregnancy Outcome in Non-obese Diabetic Mice and Wild-type Controls. Fertility and Sterility, PMC Journal - In Process.
- 2011
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Kalkunte, S., Nevers, T, Norris, W. and Sharma, S.
Vascular IL-10: A protective role in preeclampsia.
J Reprod Immunol.
PubMed Listing -
Norris, W., Nevers, T., Sharma, S. and Kalkunte, S.
Review: hCG, preeclampsia and regulatory T cells.
Placenta.
PubMed Listing -
Lai, Z., Kalkunte, S, and Sharma, S.
A critical role of interleukin-10 in modulating hypoxia-induced preeclampsia-like disease in mice.
Hypertension.
PubMed Listing -
*Robbins, J.C., Marsit, C.J., Padbury, J.F., and Sharma, S.
Endocrine disruptors, environmental
oxygen, epigenetics, and pregnancy.
Frontiers in Bioscience.
PubMed Listing - 2010
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Sharma, S., Stabila, J., Pietras, L., Singh, A. R., McGonnigal, B., Ernerudh, J., Mathhiesen,
L., and Padbury, J. F.
Haplotype-dependent differential activation of the human IL-10 gene promoter in macrophages and trophoblasts: Implications for placental IL-10 deficiency and pregnancy complications.
Am J Reprod Immunol.
PubMed Listing -
Sharma, S., Norris, W., and Kalkunte, S.
Beyond the threshold: an etiological bridge between
hypoxia and immunity in preeclampsia.
J Reprod Immunol.
PubMed Listing -
Thaxton, J and Sharma, S. Interleukin-10: A multi-faceted agent of pregnancy.
Am J Reprod Immunol.
PubMed Listing -
Thaxton, J., Nevers, T., and Sharma, S.
TLR-mediated preterm birth in response to pathogenic agents.
Infect Dis Obstet Gynecol.
PubMed Listing -
Kalkunte, S., Boij, R., Norris, W., Friedman, J., Lai, Z., Kurtis, J., Ham, K-H., Boij, R., Padbury,
J., Matthiesen, L., and Sharma, S.
Sera from preeclampsia patients elicit symptoms of human disease in mice and provide a basis for an in vitro predictive assay.
Am J Pathol.
PubMed Listing - 2009
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Thaxton, J. E., Romero, R., and Sharma, S.
TLR-9 activation coupled to IL-10 deficiency induces adverse pregnancy outcomes.
J Immunol.
PubMed Listing -
Kalkunte, S., Lai, Z., Norris, W., Pietras, L., Tewari, N., Boij, R., Neubeck, S., Markert, U.,
Sharma, S.
Novel approaches for mechanistic understanding and predicting preeclampsia.
J Reprod Immunol.
PubMed Listing -
McGowan, E.C., Kostadinov, S., McLean, K, Venturini, D., Romero, R., Laptook, A.R., Sharma, S.
Placental IL-10 dysregulation and association with bronchopulmonary dysplasia risk.
Pediatric Res.
PubMed Listing -
Bayraktarm M., Peltier, M., Vetrano, A., Arita, Y., Gurzenda, E., Joseph, A., Kazzaz, A., Sharma, S.
IL-10 modulates placental responses to TLR ligands.
Am J Reprod Immunol.
PubMed Listing -
*Tewari, N., Kalkunte, S., Murray, D.W., Sharma, S. The water channel aquaporin 1 is a novel molecular target of polychlorinated biphenyls for in utero anomalies.
J. Biol. Chem.
PubMed Listing -
Kalkunte, S., Wira, C., Sentman, C, and Sharma, S.
Vascular endothelial growth factor C facilitates immune tolerance and endovascular activity of human uterine NK cells at the maternal-fetal interface.
J Immunol.
PubMed Listing -
Murphy, S., Hanna, N.N., Fast, L., Shaw, S.K., Berg, G., Padbury, G., Romero, R., and Sharma, S.
Evidence for participation of uterine natural killer cells in the mechanisms responsible for spontaneous preterm labor and delivery
Am J Obstet Gynecol.
PubMed Listing - 2008
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Kalkunte, S., Chichester, C., Sentman, C., Romero, R., Sharma, S.
Evolution of non-cytotoxic uterine Natural Killer (uNK) cells.
Am J Reprod Immunol.
PubMed Listing -
Abrahams VM, Aldo PB, Murphy SP, Visintin I, Koga K, Wilson G, Romero R, Sharma S, Mor G.
TLR6 modulates first trimester trophoblast responses to peptidoglycan.
J Immunol.
PubMed Listing -
Gotsch, F., Romero, R., Kusanovic, J. P., Erez, O., Espinoza, J., Kim, C. J., Vaisbuch, E., Than, G. N., Mazaki-Tovi, S., Chaiworapongsa, T., Mazor, M., Bo Yoon, B. H., Edwin, S., Gomez, R., Mittal, P., Hassan, S., Sharma, S.
The anti-inflammatory limb of the immune response in preterm labor, intra-amniotic infection/inflammation and spontaneous parturition at term: A role for Interleukin-10.
J Matern Fetal Neonatal Med.
PubMed Listing -
Gustafsson C, Mjoesberg J, Matussek A, Geffers R, Matthiesen L, Berg G, Sharma S, Buer J, Ernerudh J.
Gene expression profiling of human decidual macrophages: Evidence for immunosuppressive phenotype.
PLoS One.
PubMed Listing -
Lee, H-S., Wang, Y., Maciejewski, B. S., Esho, K., Fulton, C., Sharma, S., Sanchez-Estaban, J. Interleukin-10 Protects cultured fetal rat type II epithelial cells from injury induced by mechanical stretch.
Am J Physiol Lung Cell Mol Physiol.
PubMed Listing - 2007
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Mondestin-Sorrentino, M., Smulian, J. N., Vintzileos, A. M., Sorrentino, D., Ananth, C. V., Sharma, S., Hanna, N. N.
Variations in cervical IL-10 and IL-8 concentrations throughout gestation in normal pregnancies.
Am J Reprod Immunol.
PubMed Listing -
Than, N.G., Paidas, M.J., Mizutani, S., Sharma, S., Padbury, J., Barnea, E. R.
Embryo-placento-maternal interaction and biomarkers: from diagnosis to therapy--a workshop report.
Placenta.
PubMed Listing - 2006
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Sharma, S., Murphy, S., Barnea, E.
Genes regulating implantation and fetal development: A focus on mouse knockout models.
Front Biosci.
PubMed Listing -
Tewari, N., Murphy, S.P., Sharma, S.
Genetic stress (IL-10 deficiency) and toxicant (PCB)-induced disruption of pregnancy.
Am. J. Reprod. Immunol.
Online access
2005
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Hanna, N., Bonifacio, L., Weinberger, B., Reddy, P., Murphy, S., Romero, R., Sharma, S. Evidence for Interleukin-10-mediated inhibition of cyclooxygenase-2 expression and prostaglandin production in preterm human placenta.
Am. J. Reprod. Immunol.
PubMed Listing -
Murphy, S., Fast, L., Hanna, N., Sharma, S.
Uterine NK cells mediate inflammation induced fetal demise in IL-10-null mice.
J. Immunol.
PubMed Listing -
De Paepe, M. E., Mao, Q., Chao, Y., Powell, J. L., Rubin, L. P., Sharma, S.
Hyperoxia-induced apoptosis and Fas/FasL expression in lung epithelial cells.
Am J Physiol (Lung Cell Mol Physiol)
PubMed Listing -
Clybouw C, McHichi B, Mouhamad S, Auffredou MT, Bourgeade MF, Sharma S, Leca G, Vazquez A.
EBV infection of human B lymphocytes leads to down-regulation of Bim expression: relationship to resistance to apoptosis.
J. Immunol.
PubMed Listing
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PROJECT 4: Biological Dosimetry Of Hexavalent Chromium
Anatoly Zhitkovich, Ph.D.
- 2012
- Reynolds M., Armknecht S., Johnston T. and Zhitkovich A. Undetectable role of oxidative DNA damage in cell cycle, cytotoxic and clastogenic effects of Cr(VI) in human lung cells with restored ascorbate levels. Mutagenesis 27: 437-443 (2012). PMCID: PMC3382305
- Wong V., Armknecht S. and Zhitkovich A. Metabolism of Cr(VI) by ascorbate but not glutathione is a low oxidant-generating process. J. Trace Elem. Med. Biol. 26: 192-196 (2012). PMCID: PMC3380165
- 2011
-
Zhitkovich A.
Chromium in drinking water: sources, metabolism and cancer risks.
Chem. Res. Toxicol.
PubMed Listing -
*Pietruska J.R., Liu X., Smith A., McNeil K., Weston P., Zhitkovich A., Hurt R., Kane A.B.
Bioavailability, intracellular mobilization of nickel, and HIF-1? activation in human lung epithelial cells exposed
to metallic nickel and nickel oxide nanoparticles.
Toxicol. Sci.
PubMed Listing - 2010
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Macfie, A., Hagan, E., Zhitkovich, A. Mechanism of DNA-protein cross-linking by
chromium. Chem Res Toxicol. 23(2): 341-7.
PubMed Listing -
Pietruska, J.R., Johnston, T., Zhitkovich, A, Kane A.B. XRCC1 Deficiency Sensitizes Human Lung Epithelial Cells to Genotoxicity by Crocidolite Asbestos and Libby Amphibole. Environ Health Perspect. 118: 1707-1713 (2010).
PubMed Listing - 2009
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Zecevic A., Menard H., Gurel V., Hagan E., DeCaro R. and Zhitkovich A. WRN helicase promotes repair of DNA double-strand breaks caused by aberrant mismatch repair of chromium-DNA adducts.
Cell Cycle.
PubMed Listing -
Macfie A., Hagan E. and Zhitkovich A.
Mechanism of DNA-protein cross-linking by chromium.
Chem. Res. Toxicol.
PubMed Listing - 2008
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Branco R., Chung A.P., Jonhston T., Gurel V., Morais P., Zhitkovich A.
The chromate-inducible chrBACF operon from the transposable element TnOtChr confers resistance to chromium(VI) and superoxide.
J. Bacteriol.
PubMed Listing -
Guttmann D., Poage G., Johnston T.,Zhitkovich A.
Reduction with glutathione is a weakly mutagenic pathway in chromium(VI) metabolism.
Chem. Res. Toxicol.
PubMed Listing - Reynolds M., Zhitkovich A. Ascorbate-mediated toxicity of hexavalent chromium in human cells. Metal Ions in Biology and Medicine, vol. 10, pp. 304-309. Eds. Ph. Collery, I. Maymard, L. Khassanova, T. Collery. John Libbey Eurotext, Paris (2008).
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Salnikow K., Zhitkovich A.
Genetic and epigenetic mechanisms in metal carcinogenesis and cocarcinogenesis: nickel, arsenic and chromium.
Chem. Res. Toxicol.
PubMed Listing - 2007
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*Liu, X., Gural, V., Morris, D., Murray, D., Zhitkovich, A., Kane, A.B., Hurt, R.H. Bioavailability of nickel in single-wall carbon nanotubes.
Adv. Mater.
Online access -
Reynolds M., Zhitkovich, A.
Cellular vitamin C increases chromate toxicity via a death program requiring mismatch repair but not p53.
Carcinogenesis.
PubMed Listing -
Reynolds M., Stoddard L., Bespalov I., Zhitkovich A.
Ascorbate acts as a highly potent inducer of chromate mutagenesis and clastogenesis: linkage to DNA breaks in G2 phase by mismatch repair.
Nucleic Acids Res.
PubMed Listing - 2006
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Karaczyn A., Ivanov S., Reynolds M., Zhitkovich A., Kasprzak K.S., Salnikow K.
Ascorbate depletion mediates up-regulation of hypoxia-associated proteins by cell density and nickel.
J. Cell. Biochem.
PubMed Listing -
Messer J., Reynolds M., Stoddard L., Zhitkovich A.
Causes of DNA single-strand breaks during reduction of chromate by glutathione in vitro and in cells.
Free Radic. Biol. Med.
PubMed Listing -
Quievryn, G., Messer, J., Zhitkovich A.
Lower mutagenicity but higher stability of Cr-DNA adducts formed during gradual chromate activation with ascorbate.
Carcinogenesis.
PubMed Listing
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PROJECT 5: Development of Novel Electrochemical Techniques for Heavy Metals Removal, Remediation, and Recovery
Joseph Calo, Ph.D., P.E.
- 2012
-
Calo JM, Madhavan L, Kirchner J, Bain EJ.
Arsenic Removal Via ZVI in a Hybrid Spouted Vessel/Fixed Bed Filter System.
Chem Eng J. 189–190; 237–243.
PMC3332536 - Calo, JM, Grimshaw, P, Hradil, G. “Cyclic electrowinning/precipitation (CEP) for the removal of mixtures of heavy metals from aqueous solutions,” chapter in “Novel Solutions to Water Pollution,” S. Ahuja, and K. Hristovski, eds., ACS Symposium Series, American Chemical Society, Washington, D.C., invited contribution; accepted; in press, 2012; PMID number not yet assigned.
- 2011
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Grimshaw, P., Calo, J.M., Shirvanian, P.A., Hradil, G..
II. Electrodeposition/Removal of Nickel in a Spouted Electrochemical Reactor.
Ind. Eng. Chem. Res.
PubMed Listing -
Grimshaw, P., Calo, J.M., Hradil, G..
III. Co-electrodeposition/Removal of Copper and Nickel in a Spouted Electrochemical Reactor.
Ind. Eng. Chem. Res..
PubMed Listing -
Grimshaw, P., Calo, J.M., Hradil, G. Cyclic electrowinning/precipitation (CEP) system for the removal of heavy metal mixtures from aqueous solutions.
Chemical Engineering Journal.
PubMed Listing - 2010
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Bain, EJ, Calo, JM, Spitz-Steinberg, R, Kirchner, J, Axen, J.
Electrosorption/electrodesorption of arsenic on a granular activated carbon in the presence of other heavy metals.
Energy Fuels.
PubMed Listing - 2009
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Morallon-Nunez, E, Arias-Pardilla, J, Calo, JM, Cazorla-Amoros, D.
Arsenic species interactions with a porous carbon electrode as determined with an electrochemical quartz crystal microbalance.
Electrochim. Acta.
PubMed Listing - 2007
- Bain, E., Calo, J.M. Porous materials for the adsorption/electrosorption of arsenic and chromium species from aqueous solutions. Am. Chem. Soc. Environ. Chem. Div. Preprints 47:211, 2007.
- Yao, P., Calo, J.M., Hradil, G.I. Removal of metal mixtures from aqueous solutions with a spouted particulate electrode. Am. Chem. Soc. Environ. Chem. Div. Preprints 47:207, 2007.
- 2006
- Gao, Y.-M., Calo, J.M., Hradil, G., Yao, P. Electrosorption/Electro-Desorption of Arsenic on an Activated Carbon in a Continuous Flow Cell. Proc. Carbon 2006, Paper No. SA477, Aberdeen, Scotland, 2006.
- Shirvanian, P.A., Calo, J.M., Hradil, G.I. Numerical simulation of fluid-particle hydrodynamics in a rectangular spouted vessel. Int. J. Multiphase Flow 32:739-53, 2006.
- 2005
- Shirvanian, P.A., Calo, J.M. Copper recovery in a particulate spouted bed electrode. J. Appl. Electrochem. 35:101-11, 2005.
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PROJECT 6: Nanomaterial Design for Environmental Health and Safety
Robert Hurt, Ph.D.
- 2012
- *Creighton MA, Rangel-Mendez JR, Huang J, Kane AB, Hurt, RH. Graphene Induced Adsorptive and Optical Artifacts During In Vitro Toxicology Assays Small, in press.
- *Liu J, Wang Z, Liu FD, Kane AB, Hurt RH. Chemical Transformations of Nanosilver in Biological Environments ACS Nano 6 (11), 9887–9899. PMCID3508364
- *Chen Y, Guo F, Jachak A, Kim SP, Datta D, Liu J, Kulaots I, Vaslet C, Jang HD, Huang J, Kane A, Shenoy VB, Hurt RH. Aerosol synthesis of cargo-filled graphene nanosacks. Nano Lett. 12 (4), 1996–2002. PMCID3357130
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Guo F, Silverberg G, Bowers S, Kim SP, Datta D, Shenoy V, Hurt RH.
Graphene-based environmental barriers.
Environ Sci Technol. 2012, 46 (14), 7717–7724.
PMC3415037 - Jachak A., Creighton M., Qiu Y, Kane AB, Hurt RH, “Biological Interactions and Safety of Graphene Materials”, MRS Bulletin (invited review), 37 1307-131 (2012). PMC Journal – In Process.
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Liu J, Katahara J, Li G, Coe-Sullivan S, Hurt RH.
Degradation products from consumer nanocomposites: a case study on quantum dot lighting.
Environ Sci Technol. 46 (6), 3220–3227.
PMC3362202 -
*Sanchez VC, Jachak A, Hurt RH, Kane AB.
Biological interactions of graphene-family nanomaterials: an interdisciplinary review.
Chem Res Toxicol.
PubMed listing - 2011
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Guo F, Kim F, Han TH, Shenoy VB, Huang J, Hurt RH.
Hydration-Responsive Folding and Unfolding in Graphene Oxide Liquid Crystal Phases.
ACS Nano.
PubMed listing -
*Liu, J., Pennell, K.G., Hurt, R.H.
Kinetics and Mechanisms of Nanosilver Oxysulfidation.
Environ Sci Technol.
PubMed listing -
*Liu, X., Sen, S., Liu, J. , Kulaots, I., Geohegan, D., Kane, A., Puretzkey, A.A., Rouleau, C.M., More, K.L., Palmore, G.T., Hurt, R.H.
Antioxidant Deactivation on Graphenic Nanocarbon Surfaces.
Small.
PubMed listing -
*Pietruska JR, Liu X, Smith A, McNeil K, Weston P, Zhitkovich A, Hurt R, Kane AB.
Bioavailability, intracellular mobilization of nickel, and HIF-1a activation in human lung epithelial cells exposed to metallic nickel and nickel oxide nanoparticles.
Toxicol Sci.
PubMed listing -
*Sanchez, V.C., Weston, P., Yan, A., Hurt, R.H., Kane, A.B.
A 3-dimensional in vitro model of epithelioid granulomas induced by high aspect ratio nanomaterials.
Particle and Fibre Toxicology.
PubMed listing -
*Shi X, von dem Bussche A, Hurt RH, Kane AB, Gao H.
Cell Entry of One-Dimensional Nanomaterials Occurs by Tip Recognition and Rotation.
Nat Nanotechnol.
PubMed listing - 2010
-
*Hower, J.C., Senier, C.L., Suuberg, E.M., Hurt, R.H., Wilcox, J.L., Olson, E.S.,
Mercury capture by native fly ash carbons in coal-fired power plants.
Progress in Energy and Combustion Science.
Online access -
Liu, J., Sonshine, D., Shervani, S., Hurt, R.H.,
Controlled Release of Biological Active Silver from Nanosilver Surfaces.
ACS Nano 4(11) 6903–6913 (2010).
PubMed listing -
*Liu, X., Hurt, R.H., Kane, A.B.
Biodurability of Single-Walled Carbon Nanotubes Depends on Surface Functionalization.
Carbon.
PubMed listing - 2009
-
*Sanchez VC, Pietruska JR, Miselis NR, Hurt RH, Kane AB.
Biopersistence and potential adverse health impacts of fibrous nanomaterials: What have we learned from asbestos?
Wiley Interdiscip Rev Nanomed Nanobiotechnol.
PubMed listing -
Lee B, Sarin L, Johnson NC, Hurt RH,
A nano-selenium reactive barrier approach for managing mercury over the life-cycle of compact fluorescent lamps
Environ Sci Technol.
PubMed listing -
Jakubek LM, Marangoudakis S, Raingo J, Liu X, Lipscombe D, Hurt RH.
The inhibition of neuronal calcium-ion channels by trace levels of yttrium released from carbon nanotubes,
Biomaterials.
PubMed listing -
Liu X, Vinson D, Abt D, Hurt RH, Rand DM.
Differential toxicity of carbon nanomaterials in Drosophila: Larval dietary uptake is benign but adult exposure causes locomotor impairment and mortality.
Environ Sci Technol.
PubMed listing - 2008
-
Johnson, N., Manchester, S., Sarin, L., Gao, Y., Kulaots, I., Hurt, R.H.
Mercury vapor release from broken compact fluorescent lamps and in situ capture by new nanomaterial sorbents.
Environ Sci Technol.
PubMed listing -
*Guo L, Von Dem Bussche A, Buechner M, Yan A, Kane AB, Hurt RH.
Adsorption of essential micronutrients by carbon nanotubes and its implications for nanotoxicity testing.
Small.
PubMed listing -
*Liu, X., Guo, L., Morris, D., Kane, A., Hurt, R.H.
Targeted Removal of Bioavailable Metal as a Detoxification Strategy for Carbon Nanotubes.
Carbon.
PubMed listing -
Manchester, S., Wang, X., Kulaots, I., Gao, Y., Hurt, R.H.
High capacity mercury adsorption on freshly ozone-treated carbon surfaces.
Carbon.
PubMed listing - 2007
-
*Guo, L., Liu, X., Sanchez, V., Vaslet, C., Kane, A.B., Hurt, R.H.
A window of opportunity: Designing carbon nanomaterials for environmental safety and health. Mater. Sci. Forum.
Online access -
*Guo, L., Morris, D.G., Liu, X., Vaslet C., Hurt, R.H., Kane, A.B.
Iron bioavailability and redox activity in diverse carbon nanotube samples.
Chem. Mater.
Online access -
Jian, K., Truong, T.C., Hoffman, W.P., Hurt, R.H.
Mesoporous carbons with self-assembled surfaces of defined crystal orientation.
Microporous Mesoporous Mater.
PubMed listing - *Liu, X., Gural, V., Morris, D., Murray, D., Zhitkovich, A., Kane, A.B., Hurt, R.H.G Bioavailability of nickel in single-wall carbon nanotubes. Adv. Mater. Online access
-
*Yan, A., Von Dem Bussche, A., Kane, A.B., Hurt, R.H.
Tocopheryl polyethylene glycol succinate as a safe, antioxidant surfactant for processing carbon nanotubes and fullerenes.
Carbon.
PubMed listing - 2006
-
*Hurt, R.H., Monthioux, M., Kane, A.B. Toxicology of carbon nanomaterials: status, trends, and perspectives on the special issue.
Carbon.
Online access -
*Yan, A., Lau, B.W., Weissman, B.S., Kulaots, I., Yang, N.Y.C., Kane,A.B., Hurt, R.B. Biocompatible hydrophilic supramolecular carbon nanoparticles for cell delivery.
Adv. Mater.
Online access -
Jian K, Kulaots I, Yan A, Crawford GP, Hurt, R.H.
Reconstruction and hydrophobicity of nanocarbon surfaces composed solely of graphene edges.
Carbon.
Online access
[Return to Top]
PROJECT 7: Low Concentration Vapor Exposures in Complex Systems and the Problem of Vapor Intrusion
Eric M, Suuberg, Sc.D., P.E.
- 2013
-
Yao Y, Suuberg EM. A Review of Vapor Intrusion Models.
Environ Sci Technol.
[Epub ahead of print]
PMID: 23360069 [PMC Journal - In Process] - Yao Y, Pennell KG, Suuberg EM. Simulating the effect of slab features on vapor intrusion of crack entry. Build Environ. 59:417-425. PMC3555425
- Yao Y, Shen R, Pennell KG, Suuberg EM. Examination of the US EPA’s Vapor Intrusion Database Based Upon Models. Environ Sci Technol. 2013 Feb 5;47(3):1425-33. doi: 10.1021/es304546f. Epub 2013 Jan 14. PMID: 23293835 [PMC Journal - In Process]
- Yao Y, Shen R, Pennell KG, Suuberg EM. Examination of the Influence of Environmental Factors in Contaminant Vapor Concentration Attenuation Factors Using the U.S. EPA’s Vapor Intrusion Database. Environ Sci Technol. 2013 Jan 15;47(2):906-13. doi: 10.1021/es303441x. Epub 2013 Jan 4. PMID: 23252837 [PMC Journal - In Process]
- 2012
- Dannemiller KC, Murphy JS, Dixon SL, Pennell KG, Suuberg EM, Jacobs DE, Sandel M. Formaldehyde concentrations in household air of asthma patients determined using colorimetric detector tubes. Indoor Air. 2012 Dec 24. doi: 10.1111/ina.12024. [Epub ahead of print] PMID: 23278296
-
Fu J, Rice JW, Suuberg EM.
“Phase Behavior and Crystal Structure of Binary Polycyclic Aromatic Compound Mixtures” in Crystallization Processes, Y. Mastai, Ed. , Chapter 20, pp515-538, Intech Publishing, Rijeka, Croatia, 2012.
Online access -
Fu J, Suuberg EM.
Thermochemical Properties and Phase Behavior of Halogenated Polycyclic Aromatic Hydrocarbons.
Environ Toxicol Chem.
PMID: 22139714 [PMC Journal - In Process] -
Fu J, Suuberg EM.
Vapor pressure of three brominated flame retardants determined by using the Knudsen effusionmethod.
Environ Toxicol Chem.
PMC3288591 -
Shen R, Pennell KG, Suuberg EM. A Numerical Investigation of Vapor Intrusion - The Dynamic Response of Contaminant Vapors to Rainfall Events.
Sci Total Environ.
PMID: 22922135 [PMC Journal - In Process] -
Yao Y, Pennell KG, Suuberg EM.
Estimation of Contaminant Subslab Concentration in Vapor Intrusion.
J Hazard Mater. 231-232, 10-17, 2012.
PMID: 22776832 [PMC Journal - In Process] - 2011
-
Fu J, Suuberg EM.
Solid vapor pressure for five heavy PAHs via the Knudsen effusion method.
J Chem Thermodyn.
PubMed listing -
Fu J, Suuberg EM.
Vapor pressure of solid polybrominated diphenyl ethers determined via Knudsen effusion method.
Environ Toxicol Chem.
PubMed listing -
Fu J, Suuberg EM.
Thermochemical properties and phase behavior of halogenated polycyclic aromatic hydrocarbons.
Environ Toxicol Chem.
PubMed listing - Pennell, KG, Suuberg, EM. Vapor Transport from Soil and Groundwater: Numerical Modeling Approach. In Vapor Emission to Outdoor Air and Enclosed Spaces for Human Health Risk Assessment, edited by Saponaro, S, Sezenna, E, and Bonomo, L, Nova Science Publishers, New York.
-
Rice JW, Fu J, Suuberg EM.
Thermodynamics of multicomponent PAH mixtures and development of tar-like behavior.
Ind Eng Chem Res.
PubMed listing -
Suuberg, EM, Yao, Y, Shen, R, Bozkurt, O, Pennell, KG.
Modeling Vapor Intrusion Processes and Evaluating Risks Using Subslab Data.
Environmental Health and Biomedicine, WIT Press.
Online access -
Yao Y, Shen R, Pennell KG, Suuberg EM.
Comparison of the Johnson-Ettinger vapor intrusion screening model predictions with full three-dimensional model results.
Environ Sci Technol.
PubMed listing -
Yijin J, Pennell KG, Suuberg, E.
Vapor intrusion in urban settings: effect of foundation features and source location.
Procedia Environmental Sciences.
Online access - 2010
-
J. Fu, J.W. Rice, E.M. Suuberg.
Phase behavior and vapor pressures of the
pyrene+9,10-dibromoanthracene system.
Fluid Phase Equilibrium, 298, 219-224.
PubMed listing -
J.L. Goldfarb and E.M. Suuberg.
Deviations from Ideal Sublimation Vapor Pressure Behavior in Mixtures of Polycyclic Aromatic Compounds with Interacting
Heteroatoms.
Journal of Chemical Thermodynamics, 42, 1009-1015.
Online access -
Y. Yao, K.G. Pennell, E.M. Suuberg.
The Influence of Transient Processes on
Vapor Intrusion Processes.
Paper for the AWMA Vapor Intrusion Conference, September 2010.
Online access. -
J.W. Rice and E.M. Suuberg.
Thermodynamic Study of (Anthracene plus
benzo[a]pyrene) Solid Mixtures.
Journal of Chemical Thermodynamics, 42, 1356-1360.
PubMed listing -
J.W. Rice, J. Fu, E.M. Suuberg.
Anthracene + Pyrene Solid Mixtures: Eutectic
and Azeotropic Character.
J. Chem. Eng. Data, 55, 3598-3605.
PubMed listing -
J.L. Goldfarb and E.M. Suuberg.
Vapor pressures and sublimation enthalpies of seven heteroatomic aromatic hydrocarbons measured via the Knudsen effusion technique.
Journal of Chemical Thermodynamics, 42, 781-786.
PubMed listing - 2009
-
R.M. Burgess, M.M. Perron, C.L. Friedman, E.M. Suuberg, K. G. Pennell,
M.G. Cantwell, M.C. Pelletier, K.T. Ho, J.R. Serbst, S.A. Ryba.
Evaluation of the Effects of Coal Fly Ash Amendments on the Toxicity of a Contaminated Marine
Sediment.
Env. Toxicology and Chemistry 28, 26-35.
PubMed listing -
Bozkurt, O., Pennell, K.G. Suuberg, E.M.
Simulation of the Vapor Intrusion Process for Non-Homogeneous Soils Using a Three Dimensional Numerical Model
Ground Water Monit Remediat.
PubMed listing -
Pennell KG, Bozkurt O, Suuberg EM.
Development and Application of a Three-Dimensional Finite Element Vapor Intrusion Model.
J Air Waste Manag Assoc.
PubMed listing -
Pennell KG and Suuberg EM.
Chapter 4: Vapor Transport From Soil and Groundwater: Numerical Modeling Approach. Vapor Emission to Outdoor Air and Enclosed Spaces for Human Health Risk Assessment: Site Characterization, Monitoring and Modeling. Editors: Sabrina Saponaro, Elena Sezenna and Luca Bonomo (Politecnico di Milano, Italy). Nova Science Publishers, Inc.
Online access. - 2008
-
Goldfarb, J.L., Suuberg, E.M. Raoult's Law and its application to sublimation vapor pressures of mixtures of polycyclic aromatic hydrocarbons .
Environ. Eng. Sci.
Online access -
Goldfarb, J.L., Suuberg, E.M. The effects of halogen hetero-atoms on the vapor pressures and thermodynamics of polycyclic aromatic compounds measured via the knudsen effusion technique.
J. Chem. Thermodyn.
PubMed listing -
Goldfarb, J.L., Suuberg, E.M. Vapor pressures and enthalpies of sublimation of ten polycyclic aromatic hydrocarbons determined via the knudsen effusion method.
J. Chem. Eng. Data.
Online access. -
Goldfarb, J.L., Suuberg, E.M.
Vapor pressures and thermodynamics of oxygen-containing polycyclic aromatic hydrocarbons measured using knudsen effusion.
Environ. Toxicol. Chem.
PubMed listing
[Return to Top]
PROJECT 8: Environment, Genetics And Epigenetics In A R.I. Birth Cohort (Project ended 08/31/11)
Carmen Marsit, Ph.D.
Karl Kelsey, M.D., M.O.H.
- 2011
-
Filiberto AC, Maccani MA, Wilhelm C, Gagne LA, & Marsit CJ.
Birthweight is Associated with DNA Promoter Methylation of the Glucocorticoid Receptor in Human Placenta.
Epigenetics.
PubMed listing -
Banister CE, Koestler DC, Maccani M, Padbury JF, Houseman EA, and Marsit CJ.
Infant Growth Restriction is Associated with Distinct Patterns of DNA Methylation in Human Placentas.
Epigenetics.
PubMed listing -
Maccani MA, Padbury JF, & Marsit, CJ.
miR-16 and miR-21 expression in the placenta is associated with fetal growth.
PLoS One
PubMed listing -
Wilhelm-Benartzi CS, Houseman EA, Maccani M, Poage G, Koestler DC, Langevin SM, Gagne, L, Banister, C, Padbury, JP, & Marsit, CJ.
In Utero Exposures, Infant Growth, and DNA Methylation of Repetitive Elements and Developmentally Related Genes in Human Placenta.
Environ Health Perspect.
PubMed listing - 2010
-
Avissar, M., Veiga, K., Uhl, K., Moen, E., Maccani, M., Gagne, L., & Marsit, C.J.
Bisphenol A Exposure Leads to MicroRNA Alterations in Placental Cell Lines.
Reprod Toxicol 29(4): 401-6.
PubMed listing -
Maccani, M.A., Avissar-Whiting, M., Banister, C.E., McGonnigal, B., Padbury, J.F., & Marsit, C.J.
Maternal Cigarette Smoking During Pregnancy is Associated with Downregulation of miR-16, miR-21, and miR-146a in the Placenta.
Epigenetics 5(7) (epub ahead of print).
PubMed listing -
*Robins, J.C., Marsit, C.J., Padbury, J.F., & Sharma, S.
Endocrine Disruptors, Environmental Oxygen, Epigenetics, and Pregnancy.
Frontiers in Bioscience.
PubMed listing -
Koestler, D.C., Christensen, B.C., Karagas, M.R., Bueno, R., Sugarbaker, D.J., Kelsey, K.T., Marsit, C.J., & Houseman, E.A.
Semi-Supervised Recursively Partitioned Mixture Models for Identifying Cancer Subtypes.
Bioinformatics 26(20):2578-85.
PubMed listing - 2009
-
Christensen, B.C., Houseman, E.A., Marsit, C.J., Zheng, S., Wrensch, M.R., Wiemels, J.L., Nelson, H.H., Karagas, M.R., Padbury, J.F., Bueno, R., Sugarbaker, D.J., Yeh, R.F., Wiencke, J.K., Kelsey, K.T.
Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context.
PLoS Genet.
PubMed listing -
Maccani, M.A., Marsit, C.J.
Epigenetics in in the Placenta.
Am J Reprod Immunol.
PubMed listing
[Return to Top]
CORE A: Administrative Core
Kim Boekelheide, M.D.-Ph.D.
- 2013
- Thompson, M.R. & Boekelheide, K. (2013). Multiple environmental chemical exposures to lead, mercury and polychlorinated biphenyls among childbearing-aged women (NHANES 1999-2004): Body burden and risk factors. Environmental Research. 2012 Nov 15. pii: S0013-9351(12)00288-5. doi: 10.1016/j.envres.2012.10.005. [Epub ahead of print] PMID: 23158727 [PMC Journal – In Process]
- 2012
- *Thompson M, Rice J, and Suuberg, EM. Superfund Research Program. EnviroMentor, 12, 6-8, 2012. (Not Peer Reviewed).
- 2007
- *Bozkurt, O., Pennell, K.G., Suuberg, E.M. Evaluation of characterization techniques for vapor intrusion sites using a three-dimensional computational fluid dynamics (CFD) model. AWMA Vapor Intrusion Conference Proceedings Preprints, 2007.
- *Bozkurt, O., Pennell, K.G., Suuberg, E.M. Evaluation of vapor intrusion potential using a three-dimensional computational fluid dynamics (CFD) Model. Am. Chem. Soc. Environ. Chem. Div. Preprints, 2007.
- 2009
-
*Tewari, N., Kalkunte, S., Murray, D.W., Sharma, S. The water channel aquaporin 1 is a novel molecular target of polychlorinated biphenyls for in utero anomalies.
J. Biol. Chem.
PubMed listing - 2007
-
*Liu, X., Gural, V., Morris, D., Murray, D., Zhitkovich, A., Kane, A.B., Hurt, R.H.G Bioavailability of nickel in single-wall carbon nanotubes.
Adv. Mater.
Online access - 2011
-
*Sanchez, V.C., Weston, P., Yan, A., Hurt, R.H., Kane, A.B.
A 3-dimensional in vitro model of epithelioid granulomas induced by high aspect ratio nanomaterials.
Part Fibre Toxicol.
PubMed listing -
*Pietruska JR, Liu X, Smith A, McNeil K, Weston P, Zhitkovich A, Hurt R, Kane AB.
Bioavailability, intracellular mobilization of nickel, and HIF-1? activation in human lung epithelial cells exposed to metallic
nickel and nickel oxide nanoparticles.
Toxicol Sci.
PubMed listing - 2012
-
Cordner, A, Ciplet, D, Morello-Frosch, R, Brown, P.
Reflexive Research Ethics for Environmental Health and Justice. Social Movement Studies.
Soc Mov Stud. 11(2):161-176. Epub 2012 Apr 2.
PMC3370411 -
Cohen AK., Waters, A, Brown P
Place-Based Environmental Health Justice Education:
A Community-University-Government-Middle
School Partnership
Environmental Justice 5(4): 188-197. doi:10.1089/env.2010.0021. NIHMSID 438199.
Online listing - 2010
-
Cohen, A. Achieving Healthy School Siting and
Planning Policies: Understanding Shared Concerns of Environmental
Planners, Public Health Professionals, and Educators.
New Solutions. 20(1): 49-72.
Online access - 2009
- *Hoover E., Brown P., Averick M., Kane A.B., Hurt R.H., Teaching small and thinking large: Effects of social and ethical implications in an interdisciplinary nanotechnology course. J. Nanoeducation, Volume 1, Number 1, March 2009 , pp. 86-95. NIHMS444337. Online access
- 2008
- Brown, P., Senier. L. Environmental Sociologists Help Form Local Environmental Justice Organization. Environment and Technology Section Newsletter (American Sociological Association), 2008. (Not peer reviewed.)
-
Senier, L., Hudson, B., Fort, S., Hoover, E., Tillson, R., Brown, P.
The Brown Superfund Basic Research Program: A Multistakeholder Partnership Addresses Real-World Problems in Contaminated Communities.
Environ. Sci. Technol.
PubMed listing - 2007
- Brown, P. Toxic Exposures: Contested Illnesses and the Environmental Health Movement. Columbia University Press, 2007.
- 2006
- Senier, L., Altman, R., Morello-Frosch, R., Brown, P. "Research and Action for Environmental Health and Environmental Justice: A Report on the Brown University Contested Illnesses Research Group." (Collective Behavior and Social Movements Newsletter (American Sociological Association), 2006. (Not peer reviewed.)
- 2012
-
- Campion S, Catlin N, Heger N, McDonnell EV, Pacheco SE, Saffarini C, Sandrof MA, Boekelheide K (2012) Male reprotoxicity and endocrine disruption. Toxicology Experientia Supplementum 101: 315-60. PMC Journal – in process. PMID: 22945574 [PMC Journal - In Process]
- *Sanchez VC, Jachak A, Hurt RH, Kane AB. (2012) Biological interactions of graphene-family nanomaterials: an interdisciplinary review. Chem Res Toxicol. 13;25(1):15-34. PMC3259226
- Campion SN, Catlin N, Houseman EA, Hensley J, Sui Y, Gaido KW, Wu Z, Boekelheide K (2012) Molecular alterations underlying the enhanced disruption of spermatogenesis by 2.5-hexanedione and carbendazim co-exposure. Reprod Toxicol. 33: 382-9. PMC3327768
- Cordner A, Ciplet D, Brown P, Morello-Frosch R (2012) Reflexive research ethics for environmental health and justice: academics and movement-building. Soc Mov Stud. 11: 161-176. PMC3370411
- Cordner A (2012) The health care access and utilization of homeschooled children in the United States. Soc Sci Med. 75: 269-73, PMID: 22534378 [PMC Journal - In Process]
- Hoover E, Cook K, Plain R, Sanchez K, Waghiyi V, Miller P, Dufault R, Sislin C, Carpenter DO (2012) Indigenous peoples of north america: environmental exposures of reproductive justice. Environ Health Perspect 120: 1645-9. PMC3548285
- Houseman EA, Accomando WP, Koestler DC, Christensen BC, Marsit CJ, Nelson HH, Wiencke JK, Kelsey KT (2012) DNA methylation arrays as surrogate measures of cell mixture distribution. BMC Bioinformatics 13:86. PMC Journal - in process. PMC3532182
- Keller DA, Juberg DR, Catlin N, Farland WH, Hess FG, Wolf DC, Doerrer NG (2012) Identification and characterization of adverse effects in 21st century toxicology. Toxicol Sci 126: 291-7. PMC3307604
- Koestler DC, Marsit CJ, Christensen BC, Accomando W, Langevin SM, Houseman EA, Nelson HH, Karagas MR, Wiencke JK, Kelsey KT (2012) Peripheral blood immune cell methylation profiles are associated with nonhemtopoietic cancers. Cancer Epidemiol Biomarkers Prev. 21: 1293-302. PMC3415587
- Langevin SM, Koestler DC, Christensen BC, Butler RA, Wiencke JK, Nelson HH, Houseman EA, Marsit CJ, Kelsey KT (2012) Peripheral blood DNA methylation profiles are indicative of head and neck squamous cell carcinoma: an epigenome e-wide association study. Epigenetics 7: 291-9. PMC3335952
- Marsit CJ, Lambertini L, Maccani MA, Koestler DC, Houseman EA, Padbury JF, Lester BM, Chen J (2012) Placenta-imprinted gene expression association of infant neurobehavior. J. Pediatr. 160: 854-860.e2. PMC3311768
- Shen R, Pennell KG and Suuberg EM (2012) A numerical investigation of vapor intrusion – The dynamic response of contaminant vapors to rainfall events. Sci Total Environ 437C: 110-120, PMC Journal - In Process. PMID: 22922135 [PubMed - in process]
- Wilhelm-Benartzi CS, Houseman EA, Maccani MA, Poage GM, Koestler DC, Langevin SM, Gagne LA, Banister CE, Padbury JF, Marsit CJ (2012) In utero exposures, infant growth, and DNA methylation of repetitive elements and developmentally related genes in human placenta. Environ Health Perspect. 120: 296-302. PMC3279448
- 2011
- Avissar-Whiting M, Koestler DC, Houseman EA, Christensen BC, Kelsey KT, Marsit CJ. Polycomb group genes are targets of aberrant DNA methylation in renal cell carcinoma. Epigenetics, 2011. PMC3230543
- Banister CE, Koestler DC, Maccani MA, Houseman EA, Padbury JF, and Marsit CJ. Infant growth is associated with distinct patterns of DNA methylation in human placentas. Epigenetics, 2011. PMC3154432
- Brown P, Cordner A. Lessons learned from flame retardant use and regulation could enhance future control of potentially hazardous chemicals. Health Aff (Millwood). 2011 May;30(5):906-14. PMID:21555474 PMC Journal – In Process
- Christensen BC, Smith A, Zheng S, Koestler DC, Houseman EA, Marsit CJ, Wiemels JL, Nelson HN, Karagas MR, Wrensch MR, Kelsey KT, Wiencke JK. DNA Methylation, Isocitrate Dehydrogenase Mutation, and Survival in Glioma. Journal of the National Cancer Institute, 2011. PMC3022619
- Filiberto AC, Maccani MA, Koestler DC, Wilhelm-Benartzi C, Gagne LA, Marsit CJ. Birthweight is associated with DNA promoter methylation of the glucocorticoid receptor in human placenta. Epigenetics, 2011. PMC3121971
- Ito H, Matsuo K, Tanaka H, Koestler DC, Ombao H, Fulton J, Shibata A, Fujita M, Sugiyama H, Soda M, Sobue T, and Mor V. Non-filter and filter cigarette consumption and the incidence of lung cancer by histological type in Japan and the United States: analysis of 30-year data from population based cancer registries. International Journal of Cancer, 2011. PMID: 20589676 [PMC Journal – In Process]
- Marsit CJ, Koestler DC, Christensen BC, Karagas MR, Houseman EA, Kelsey KT. DNA methylation array analysis identifies profiles of blood-derived DNA methylation associated with bladder cancer. Journal of Clinical Oncology. 29(9):1133-9, 2011. PMC3083868
- Wilhelm-Benartzi C, Christensen BC, Koestler DC, Houseman EA, Wiencke JK, Schned AR, Karagas MR Kelsey KT, Marsit CJ. Association of second hand smoke exposure on DNA methylation in bladder cancer cases. Cancer Causes and Control. 2011. PMC3140591
- 2010
- Fu, J., Rice, J.W., Suuberg, E.M. Phase Behavior and Vapor Pressures of the Pyrene + 9,10-Dibromoanthracene System. Fluid Phase Equilibrium, 298, 219-224, 2010. PMC2976556
- Gee GV, Koestler DC, Christensen BC, Sugarbaker DJ, Ugolini D, Ivaldi GP, Resnick MB, Houseman EA, Kelsey KT, and Marsit CJ. Downregulated MicroRNAs in the differential diagnosis of malignant pleural mesothelioma. International Journal of Cancer, 2010. PMC2911512
- Koestler DC, Marsit CJ, Christensen BC, Karagas MR, Bueno R, Sugarbaker DJ, Kelsey KT, and Houseman EA. Semi-Supervised Recursively Partitioned Mixture Models for Identifying Cancer Subtypes. Bioinformatics, 2010. PMC2951086 PMC2951086
- Liu X, Hurt RH, Kane AB: Biodurability of single-walled carbon nanotubes depends on surface functionalization. Carbon 48: 1961-1969 2010. PMC2844903
- Rice, J.W., Fun, J., Suuberg, E.M. Anthracene + Pyrene Solid Mixtures: Eutectic and Azeotropic Character. J. Chem. Eng. Data, 55, 3598-3605, 2010. PMC2992339
- Rice, J.W., Suuberg, E.M. Thermodynamic Study of (Anthracene + Benzo[a]Pyrene) Solid Mixtures. Journal of Chemical Thermodynamics, 42 (11), 1356-1360, 2010. PMC2929985
- Wilhelm-Benartzi C, Koestler DC, Houseman EA, Christensen BC, Wiencke JK, Schned AR, Karagas MR Kelsey KT, Marsit CJ. DNA methylation profiles delineate etiologic heterogeneity and clinically important subgroups of bladder cancer. Carcinogenesis, 2010. PMC2966555
- 2009
- *Hoover E., Brown P., Averick M., Kane A.B., Hurt R.H., Teaching small and thinking large: Effects of social and ethical implications in an interdisciplinary nanotechnology course. J. Nanoeducation, Volume 1, Number 1, March 2009 , pp. 86-95. NIHMS444337. Online access
-
Jakubek L, Marangoudakis S, Raingo J, Liu X, Lipscombe D, Hurt RH.
The inhibition of neuronal calcium-ion channels by trace levels of yttrium released from carbon nanotubes.
Biomaterials. 2009 Oct;30(31):6351-7. doi: 10.1016/j.biomaterials.2009.08.009. Epub 2009 Aug 20.
PMC2753181 -
Liu X, Abt D., Vinson, D., Hurt, RH., Rand, D.
Differential toxicity of carbon nanomaterials in Drosophilia: Larval dietary uptake in benign but adult exposure causes locomotor impairment and mortality.
Environ. Sci. Technol. 2009 Aug 15;43(16):6357-63.
PMC3147226 - 2008
- * Guo, L., Van Dem Bussche, A., Buechner, M., Kane, A.B., Hurt, R.H. Adsorption of essential micronutrients by carbon nanotubes and its implications of nanotoxicology testing, Small 2008 Jun;4(6):721-7. doi: 10.1002/smll.200700754 PMC3209620
- Senier, L., Brown, P., Hudson, B., Fort, S., *Hoover, E., Tilson, R., Brown Superfund Basic Research Program: A multistakeholder partnership addresses real-world problems in contaminated communities. Environ Sci Technol. 2008 Jul 1;42(13):4655-62. PMC2504735
- 2007
- Averick, M., Brown, P., * Hoover, E. Prometheus: -9 Implications of nanotechnology as perceived by nanoscientists. J. Nanoethics, submitted.
- * Guo, L., Liu, X., Sanchez, V., Vaslet, C., Kane, A.B., Hurt, R.H. A window of opportunity: Designing carbon nanomaterials for environmental safety and health. Mater. Sci. Forum 544/545:511-516, 2007.
- * Guo, L., Morris, D.G., Liu, X., Vaslet, C., Hurt, R.H., Kane, A.B. Iron bioavailability and redox activity in diverse carbon nanotube samples. Chem. Mater. 19:3472-78, 2007.
- *Sui Y and Wu Z (2007) Alternative statistical parameter for high-throughput screening assay quality assessment. J Biomol Screen. 2007 Mar;12(2):229-34. Epub 2007 Jan 11. PMID: 17218666
- Tewari, N., Kalkunte, S., *Thaxton, J., and Sharma, S. Polychlorinated biphenyls (PCBs) and female reproductive health: An enigmatic paradigm. ISSRF Proceedings, in press.
- Wu Z, Liu D and *Sui Y. Quantitative Assessment of Hit Detection and Confirmation in Single and Duplicate HTS Screenings. J Biomol Screen. 2008 Feb;13(2):159-67. PMID: 18216390
- *Yao, P., Calo, J.M., Hradil, G.I. Removal of metal mixtures from aqueous solutions with a spouted particulate electrode. Am. Chem. Soc. Environ. Chem. Div. Preprints 47:207, 2007.
- 2006
- Gao Y-M, Calo J.M., Hradil G., Yao P. Electrosorption/Electro-Desorption of Arsenic on an Activated Carbon in a Continuous Flow Cell. Proc. Carbon 2006, Paper No. SA477, Aberdeen, Scotland, 2006.
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CORE B: Research Translation Core
Eric M, Suuberg, Sc.D., P.E.
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CORE C: Analytical Core
David Murray, Ph.D.
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CORE D: Molecular Pathology Core
Mary Hixon, Ph.D. (04-18-05 - 06-30-12)
Robbert Creton, Ph.D. (07-01-12 - present)
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CORE E: Community Outreach Core — Environmental Health and Justice
Phil Brown, Ph.D.
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CORE F: Training Core
Agnes Kane, M.D.-Ph.D.
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