Brown University School of Engineering

Joint Materials/Solid Mechanics Seminar Series “Mechano-Adaptation in Vascular Tissues”

Add event to my Google calendar Add event to my Google calendar Share this event on facebook E-mail this event
Monday, September 10, 2012 4:00pm - 5:00pm

BROWN UNIVERSITY Joint Materials/Solid Mechanics Seminar Series “Mechano-Adaptation in Vascular Tissues” Patrick Alford Department of Biomedical Engineering University of Minnesota ABSTRACT: Because arteries exist in a dynamic mechanical environment, they must rapidly respond to changes in external forces to maintain mechanical homeostasis. Though this adaptive response plays a key role in cardiovascular maintenance, maladaptive growth and remodeling have been implicated in a number of vascular dysfunctions. In this talk, I will describe elasticity-based theoretical approaches and tissue-engineered experimental models for elucidating the pathways leading from applied mechanical stress to vascular mechano-adaptation. These approaches will then be applied to better understand the dynamics of vascular remodeling in hypertension and traumatic cerebral vasospasm. Monday, September 10, 2012 4:00-5:00 pm B&H 190