Faculty Profile: Raymond Niaura, PHD

Raymond Niaura
Raymond Niaura, PHD
Professor of Psychiatry & Human Behavior
Psychiatry & Human Behavior
Raymond Niaura, Ph.D., is a professor of psychiatry and human behavior at Brown Medical School and Butler Hospital. He is the Director of Transdisciplinary Research. His primary areas of responsibility lie in being an independently funded researcher and faculty mentor to predoctoral interns, postdoctoral fellows, and junior faculty. Research interests include tobacco dependence and psychological factors affecting metabolism and cardiovascular diseases.

Institutions

MH

Research Description

Raymond Niaura, Ph.D., is a professor of psychiatry and human behavior at Brown Medical School and Butler Hospital.

Niaura's research interests fall into two broad areas: 1) smoking cessation and tobacco dependence, with a focus on combined pharmacological and behavioral treatments for smoking cessation, and 2) investigating biobehavioral mechanisms related to tobacco dependence. He also has a long-standing interest in the role that cue reactivity plays in precipitating relapse to smoking.

Current research focuses on:
• Examining the incremental efficacy of adding behavioral treatment to the nicotine patch among Medicare patients in inner city primary medical care clinics.
• Evaluating the efficacy of the patch as treatment for HIV+ smokers.
• Examining a family-based strategy for prevention of uptake of smoking among youth (nine - twelve years), seen in pediatric primary care clinics.
• Determining whether subgroups of smokers are more or less responsive to bupropion based on their current and past profile of depressive symptoms and polymorphisms in certain candidate genes.
• Determining how psychiatric comorbidities influence tobacco use uptake trajectories in youth.

Niaura is currently PI of the Medicare Stop Smoking Program (MSSP), a demonstration project funded by the Centers for Medicare and Medicaid Services. The results of the MSSP will have direct bearing on the first ever creation of a preventive behavioral health benefit for seniors enacted by Congress. Altogether, Niaura has served as principal investigator or co-investigator of 32 National Institutes of Health (NIH) grants, as well as numerous grants from other funding agencies, including serving as PI of 14 on-going or completed multi-center, industry-sponsored pharmacological smoking cessation trials.

Niaura has served as a member of the Behavioral Medicine Study Section at NIH and as an ad hoc reviewer on several other study sections. He was part of the subcommittee on psychological factors affecting physical condition for DSM IV, as well as part of the National Heart, Lung, and Blood Institute (NHLBI) task forces on Smoking and Body Weight, and Biobehavioral Mechanisms in Atherosclerosis. Niaura is currently Associate Editor for Nicotine and Tobacco Research. He is a fellow of the American Psychological Association, the Society for Behavioral Medicine, and the American Academy of Health Behavior. He is President Elect of the Society for Research on Nicotine and Tobacco (SRNT).

Grants and Awards

Fellow, American Psychological Association, 2003.

Invited Presentation: "What can the cue exposure paradigm tell you about drug craving: The example of tobacco." Presented at the Department of Psychiatry and Human Behavior, Sixth Annual Research Symposium on Mental Health Sciences, Brown Medical School, Providence, RI. March, 2002.

Secretary/Treasurer, Society for Research on Nicotine and Tobacco, 2002.

Fellow, Society of Behavioral Medicine, 2001 - present.

Affiliations

1986-present Society of Behavioral Medicine (Fellow)

1988-present American Psychological Association
--Division 12, Clinical Psychology
--Division 38, Health Psychology
--Division 28, Psychopharmacology (Fellow)
--Division 50, Addictive Behaviors

1988-present American Psychosomatic Society

1989-1992 Association for the Advancement of Behavior Therapy

1991-1995 American Association for the Advancement of Science

1992-present American Psychological Society

1994-present Society for Research on Nicotine and Tobacco (Charter Member)

2001-present Member, American Academy of Health Behavior. (Fellow)

Funded Research

1. Goldstein, M.G., and Niaura, R.S. (Co-PI). Schedule of nicotine gum administration and smoking cessation.
Institutional Research Grant of the American Cancer Society, 7/85 - 8/86. Total costs: $7,500.

2. Niaura, R. (PI), Korr, K., Follick, M., Ahern, D., and Gorkin, L.
Hostility and coronary artery disease: The mediating role of cardiovascular reactivity during behavioral challenge.
Biomedical Research Support Grant, National Institutes of Health (NIH), 5/86 - 4/88. Total costs: $8,300.

3. Abrams, D.B., Monti, P., Pinto, R., Follick, M.J., Goldstein, M., and Niaura, R.S. Psychosocial stressors, smoking cessation, and cardiovascular risk.
National Heart, Lung, and Blood Institute (NHLBI), R01HL32318, 9/86 - 9/89. Total direct costs: $465,418.

4. Goldstein, M.G., and Niaura, R.S. (Co-PI). Self-help smoking cessation and nicotine dependence.
National Cancer Institute (NCI), R03CA44022, 9/86 - 8/87. Total direct costs: $35,000.

5. Follick, M.J., Gorkin, L., Niaura, R.S., and Steinberg, J. Interventional trial among Type II diabetics with borderline hypertension.
Rhode Island Department of Health, 4/87 - 3/88. Total direct costs: $50,000.

6. Gorkin, L., Follick, M.J., Norvell, N., Charles, E., Rosen, R., Niaura, R., Capone, R., Rogers, W., and Kostis, J. Quality of life in congestive heart failure.
Merck, Sharp and Dohme, 7/87 - 4/88. Total direct costs: $108,000.

7. Gorkin, L., Alberti, K., Follick, M.J., Niaura, R., Ahern, D.K., Goldstein, M.G., and Capone, R. CAST experimental assessment of suppressor enrollment.
Clinical Trials Branch, NHLBI, RFANIH-87-H-09-P, 1987 - 1990. Total direct costs: $386,706.

8. Niaura, R. (PI), Emmons, K., and Abrams, D. The implications of pulmonary feedback in the prevention of smoking cessation relapse.
American Lung Association, 7/88 - 6/90. Total direct costs: $34,293.

9. Niaura, R. (PI). Effects of a psychosocial stress manipulation on levels of lipids and lipoproteins in Cercopithecus Aethiops.
Biomedical Research Support Grant, NIH SO7RR05818, 8/88 - 7/89. Total costs: $4,570.

10. Abrams, D.B., DePue, J. (Co-PI), Niaura, R.S. (Co-PI), Goldstein, M.G., Medeiros, M., Follick, M., and Gorkin, L. High blood pressure/diabetes treatment program.
Rhode Island Department of Health, 9/88 - 9/89. Total direct costs: $66,000.

11. Goldstein, M.G., Niaura, R.S. (Co-PI), and Dubé, C. (Co-PI). Physician adoption of smoking protocols.
NCI, P01CA50087, 7/89 - 6/94. Total direct costs: $2,064,000.

12. Niaura, R. (PI), Thompson, P., Herbert, P., and Sady, S. High-density lipoprotein cholesterol during smoking cessation.
Biomedical Research Support Grant, NIH SO7RR05818, 8/89 - 7/90. Total direct costs: $7,480.

13. Goldstein, M.G., Niaura, R.S. (Co-PI), and Abrams, D.B. Efficacy of clonidine as an aid to smoking cessation.
National Institute of Drug Abuse (NIDA), R01DA05623, 9/89 - 9/92. Total direct costs: $329,103.

14. Niaura, R. (PI), Abrams, D., Velicer, W., et al. Nicotine dependence and smoking relapse.
NHLBI, R01HL32318, 4/91 - 3/94. Total direct costs: $460,000.

15. Monti, P.M., Rohsenow, D.J., Abrams, D.B., Niaura, R.S., and Sirota, A. Smoking, alcoholics' reactivity, and treatment motivation.
National Institute of Alcohol Abuse and Alcoholism (NIAAA), 7/91 - 6/96. Total direct costs: $1,336,249.

16. Stoney, C., Niaura, R., Bausserman, L., Flynn, M., and Marcus, B. Effects of behavioral challenge on lipids and lipoproteins.
NHLBI, 9/91 - 8/94. Total direct costs: $816,768.

17. Rohsenow, D., Monti, P., Sirota, A., Rubonis, A., Abrams, D., and Niaura, R. Smoking's effect on elicited reactions to alcohol cues among alcoholics.
Veterans Administration (VA) Merit Review Award, 4/92 - 3/95. Total direct costs: $287,320.

18. Niaura, R. (PI), Stoney, C., Bausserman, L., and Flynn, M. Coping style, stress responsiveness, and lipids.
NHLBI, R01HL46611, 4/92 - 3/96. Total direct costs: $813,281.

19. McGarvey, S., Bausserman, L., and Niaura, R. Lipid profiles, adiposity, and psychosocial factors among modernizing Samoans.
Miriam Hospital Foundation, 7/92 - 6/93. Total direct costs: $14,000.

20. Engebretson, T., Tilkemeier, P., Niaura, R., and Stoney, C. Emotions, behaviors, and coronary heart disease.
Department of Psychiatry and Human Behavior, Brown University, 9/92 - 8/93. Total direct costs: $8,200.

21. Niaura, R. (PI). Coping style, stress responsiveness, and lipids: Minority postdoctoral research supplemental award.
NHLBI, HL46611-01A1S1, 9/92 - 4/95. Total direct costs: $107,387.

22. Brown, R., Miller, I., Goldstein, M., Abrams, D., Niaura, R., and Murphy, J. Coping with depression in smoking cessation.
NIDA, 12/92 - 11/96. Total direct costs: $1,450,502.

23. Monti, P.M., Swift, R., Rohsenow, D., Abrams, D., Gulliver, S., and Niaura, R. Coping, exposure and naltrexone treatment with alcoholics.
NIAAA, 6/94 - 5/99. Total direct costs: $1,281,433.

24. Goldstein, M., Niaura, R., DePue, J., Rakowski, W., and Wiley, C. Promoting cancer prevention in primary care.
NCI, 7/94 - 6/99. Total direct costs: $1,374,654.

25. Niaura, R. (PI). Effects of a high fat diet on plasma lipoprotein concentrations. Department of Psychiatry and Human Behavior, Brown University, 7/95 - 6/96. Total costs: $13,000.

26. Niaura, R. (PI), Goldstein, M., Abrams, D., Emmons, K., Brown, R., Fagan, M., Sweeney, P., and Hardiman, J. Motivation and patch treatment for underserved smokers.
NIDA, 7/96 - 6/99. Total costs: $1,586,476.

27. Abrams, D. (PI), Niaura, R., Goldstein, M., Emmons, K., Borrelli, B., Brown, R., Swift, R., Stout, R., Monti, P., Rohsenow, D., Colby, S., and Shepard, D. Motivating alcoholics to quit smoking.
NIAAA, 7/96 - 6/01. Total costs: $3,099,465.

28. Niaura, R. (PI), Abrams, D., and Goldstein, M. Matching antidepressant treatment for smoking cessation.
NHLBI, 7/97 - 6/02. Total costs: $1,548,724.

29. Brown, R., Miller, I., Goldstein, M., Niaura, R., and Abrams, D. Coping with depression in smoking cessation.
NIDA, 7/97 - 6/01. Total costs: $1,983,952.

30. Brown, R., Niaura, R., Goldstein, M., and Abrams, D. Smoking cessation in teens with comorbid psychopathology.
NCI, 9/97 - 9/01. Total direct costs: $1,847,469.

31. Brown, R., Monti, P., Abrams, D., and Niaura, R. Efficacy of depression skills treatment with alcoholics.
NIAAA, 7/97 - 6/01. Total costs: $1,885,712.

32. Flanigan, T., Goldstein, M., Niaura, R., and Pugatch, D. HIV and STD intervention research for young men in prison.
Centers for Disease Control and Prevention (CDC), 9/97 - 8/02. Total costs: $1,135,841.

33. Rohsenow, D., Monti, P., and Niaura, R. Naltrexone and nicotine replacement effects on cue reactivity of smokers.
VA Merit Review Grant, 12/97 - 12/01. Total costs: $404,800.

34. DePue, J., Goldstein, M., Niaura, R., Kazura, A., Becker, B., and Santucci, K. Helping parents in the pediatric ER to quit smoking.
NCI, 4/97 - 3/01. Total costs: $709,018.

35. Bock, B., Becker, B., Niaura, R., and Partridge, R. Smoking cessation in the chest pain observation unit.
Department of Psychiatry Research Support Grant, Brown University School of Medicine, 1998 – 1999. Total costs: $12,500

36. Shadel, W.G., Niaura, R., Abrams, D.B., and Goldstein, M.G. Information processing and cue reactivity between motivated and non-motivated smokers.
American Cancer Society, 1/98 – 7/99. Total costs: $10,000.

37. Marcus, B., Abrams, D., Parisi, A., Albrecht, A., King, T., and Niaura, R. Moderate exercise to aid smoking cessation in women.
NCI, 4/98 – 3/02. Total costs: $1,284,961.

38. Niaura, R. Infrastructure support for the Division of Behavioral and Preventive Medicine.
Department of Psychiatry and Human Behavior Research Award, Brown University, 7/98 – 6/99. Total costs: $12,500.

39. Niaura, R., Goldstein, M., Kazura, A., DePue, J., and Bock, B. Immunizing against tobacco use in pediatric health care.
NIDA, 9/98 - 12/02. Total costs: $1,468,289.

40. Bock, B., Niaura, R., Becker, B., Goldstein, M., Partridge, R., and Tammaro, D. Smoking cessation in the emergency department.
American Heart Association, 1/99 - 2/01.Total costs: $500,000.

41. Niaura, R., Shadel, W., Goldstein, M., Abrams, D., Flanigan, T., Morrow, K., Tashima, K., Stein, M., Stone, J., and Shepard, D. Motivation and patch treatment for HIV+ smokers.
NIDA, 1/99 - 12/04. Total costs: $2,519,197.

42. Shadel, W.G., Niaura, R., Abrams, D.B., and Cervone, D. A social cognitive theory of smoking and cessation.
NCI, 4/99 – 3/02. Total costs: $587,886.

43. Hutchison, K., Niaura, R., Shadel, W.G., and McClelland, G. Psychophysiological and behavioral mechanisms of smoking.
NCI, 7/99 – 6/01.

44. Borrelli, B., McQuaid, E., Becker, B., Abrams, D., Hammond, K., Fritz, G., Niaura, R., and Natarajan, R. Motivating parents of kids with asthma to quit smoking.
NHLBI, 4/99 – 3/03. Total costs: $1,903,603.

45. Bock, B., Niaura, R., Sciamanna, C., Becker, B., Partridge, R., Tammaro, D., Papandonatos, G., and Neighbors, C. Smoking cessation interventions in the chest pain observation unit.
NHLBI, 8/99 - 6/03. Total costs: $1,377,260.

46. Shadel, W.G., Niaura, R. and Abrams, D.B. Adolescent social cognition and cigarette advertising.
NIDA, 9/99 – 8/01. Total costs: $156,191.

47. Abrams, D.B., Niaura, R., et al. Nicotine dependence: Risk and recovery over generations.
NCI and NIDA Specialized Program of Research Excellence (SPORE), 10/99 – 9/04. Total costs: $11,582,454.

48. Niaura, R., Bock, B. Lloyd, E., Buka, S., Brown, R., and Lipsitt, L. Adolescent progression of nicotine dependence. Project 2 of SPORE
NCI and NIDA. 10/99 - 9/04. Total costs: $1,387,924.

49. Brown, R, Niaura R., Price, L, Carpenter L., Lejuez, C., Kahler, C., Stroud, L. Biobehavioral Vulnerability to Early Smoking Relapse.
NCI, 9/00 – 8/01. Total costs: $362,500.

50. Becker, B., Bock, B., Niaura, R., Lester, B. Smoking Cessation in Mothers and Other Household Members of Babies Being Treated in the Special Care Nursery.
Robert Wood Johnson Foundation. 9/00 – 8/02. Total costs: $192,648.

51. Stein, M., Niaura, R. (Co-PI) and Shadel, W. Smoking cessation among methadone maintained patients.
NCI, 6/01-5/05. Total costs: $2,000,000.

52. Abrams, D., et al. (Niaura, R., Co-I). Transdisciplinary cancer control research training grant.
NCI. 7/01 – 6/07. Total costs: $2,671,251.

53. Niaura, R., et al. Prenatal neuroendocrine mediators of young adult smoking.
National Institute of Child Health and Human Development (NICHD). 6/03-5/05. Total costs: $432,103.

54. Niaura, R., Stanton, C., Lloyd-Richardson, E., Morrow, K., Neighbors, C., Tashima, K., Flanigan, T. Reducing ethnic health disparities: Motivating HIV + Latinos to quit smoking.
NIDA, 8/05-8/10. Total costs: $2,970,209.

55. Niaura, R. Transdisciplinary Tobacco Use Research Center (TTURC) Nicotine Dependence: Phenotype, Endophenotype and Contexts.
NCI. 8/04-8/09. Total costs: $8,626,255.