Research

Progress on detecting glucose levels in saliva

Dealing with the 1 percent

A plasmonic interferometer can detect glucose molecules in water. Detection of glucose in a complex fluid is more challenging. Controlling the distance between grooves and using dye chemistry on glucose molecules allows researchers to measure glucose levels despite the 1 percent of saliva that is not water.

Researchers at Brown have developed a new biochip sensor that that can selectively measure glucose concentrations in a complex fluid like saliva. Their approach combines dye chemistry with plasmonic interferometry. A dependable glucose monitoring system that uses saliva rather than blood would be a significant improvement in managing diabetes.