Research

Compound stymies polyomaviruses in lab

Retro-2

Other substances can control the polyoma virus only if they were administered prior to infection. In cell culture studies, Retro-2 appears to control the infectivity and spread of polyomavirus even when the virus is already established. Credit: Atwood lab/Brown University

There is no approved medicine to treat polyomaviruses, which afflict people with weakened immune systems, but scientists have found that a chemical compound called Retro-2 is able to reduce significantly the infectivity and spread of the viruses in lab cell cultures. Now they are working to improve it.